Gisvold J J, Reese D F, Karsell P R
AJR Am J Roentgenol. 1979 Dec;133(6):1143-9. doi: 10.2214/ajr.133.6.1143.
Breasts of 724 patients were studied by physical examination, mammography, and computed tomographic mammography (CTM) using a scanner designed for evaluation of the breast. Among cases in which CTM was not accompanied by use of contrast material, there were 60 malignant lesions, of which 10% were missed by mammography, 32% by CTM, and 8% by both. Among cases where CTM was supplemented by a 50 ml injection of 75% contrast material, there were 63 malignant lesions, of which 14% were missed by mammography, 16% by CTM, and 3% by both. Among cases where CTM was supplemented by a 300 ml infusion of 30% contrast material, there were 41 malignant lesions, of which 7% were missed by mammography and 5% by CTM, but none by both. Clinically, 22% of the malignant lesions in the infusion series were occult. There were 44 benign lesions in patients studied with the infusion technique. With mammography 68% were suspicious for malignancy, and with CTM, 56%.
使用专为乳腺评估设计的扫描仪，通过体格检查、乳房X线摄影和计算机断层乳腺摄影（CTM）对724例患者的乳房进行了研究。在未使用造影剂的CTM检查病例中，有60例恶性病变，其中乳房X线摄影漏诊10%，CTM漏诊32%，两者均漏诊8%。在CTM检查中补充注射50毫升75%造影剂的病例中，有63例恶性病变，其中乳房X线摄影漏诊14%，CTM漏诊16%，两者均漏诊3%。在CTM检查中补充输注300毫升30%造影剂的病例中，有41例恶性病变，其中乳房X线摄影漏诊7%，CTM漏诊5%，两者均无漏诊。临床上，输注系列中22%的恶性病变为隐匿性。采用输注技术研究的患者中有44例良性病变。乳房X线摄影显示68%可疑为恶性，CTM显示56%可疑为恶性。
