Altehoefer C, Ghanem N, Högerle S, Moser E, Langer M
Department of Diagnostic Radiology, University Hospital Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany.
Eur J Radiol. 2001 Oct;40(1):16-23. doi: 10.1016/s0720-048x(01)00313-8.
to evaluate the comparative impact of magnetic resonance imaging and bone scintigraphy in bone metastases of breast cancer.
in 81 patients with histologically proven breast cancer magnetic resonance imaging of the axial skeleton and whole-body bone scintigraphy had been performed. Images were retrospectively reviewed and compared for detection of metastases, extent of metastatic disease and therapeutic implications according to the patients' records.
about 54/81 (67%) patients revealed bone metastases. In 7/54 (13%) patients with bone metastases, scintigraphy was false negative. In one patient a solitary sternal metastases was seen. In 26/53 [49%] patients with spinal metastases, magnetic resonance imaging showed more extensive disease. Local radiotherapy or surgery was indicated in ten patients with metastases not evident in bone scintigraphy, in 20 patients with positive results by both imaging modalities and in six patients with metastases of pelvis imaged by bone scintigraphy only.
magnetic resonance imaging of the axial skeleton and pelvis appears superior for staging as only one patient had metastases merely outside the axial skeleton and local therapy was indicated even in spinal regions negative in bone scintigraphy.
评估磁共振成像和骨闪烁显像在乳腺癌骨转移中的比较影响。
对81例经组织学证实的乳腺癌患者进行了轴向骨骼的磁共振成像和全身骨闪烁显像。根据患者记录，对图像进行回顾性分析，比较转移灶的检测、转移疾病的范围及治疗意义。
81例患者中约54例（67%）显示有骨转移。在54例有骨转移的患者中，7例（13%）骨闪烁显像为假阴性。1例患者可见孤立的胸骨转移灶。在53例有脊柱转移的患者中，26例（49%）磁共振成像显示疾病范围更广。10例骨闪烁显像未显示转移灶的患者、20例两种成像方式结果均为阳性的患者以及6例仅通过骨闪烁显像发现骨盆转移的患者接受了局部放疗或手术。
轴向骨骼和骨盆的磁共振成像在分期方面似乎更具优势，因为仅1例患者的转移灶仅位于轴向骨骼之外，即使在骨闪烁显像为阴性的脊柱区域也提示了局部治疗。
