Al Rajeh S, Awada A, Bademosi O, Ogunniyi A
Division of Neurology, King Saud University, Riyadh, Saudi Arabia.
Seizure. 2001 Sep;10(6):410-4. doi: 10.1053/seiz.2001.0602.
To determine the prevalence of epilepsy and other convulsive disorders and the causes of symptomatic epilepsies in a Saudi Arabian population.
Door to door survey of a restricted area inhabited by 23 700 Saudi nationals. The World Health Organization (WHO) protocol designed to detect neurological disorders was used as screening instrument. All patients with probable seizures were examined by a neurologist and 92% of positive cases were investigated by brain computed tomography (CT) and electroencephalogram (EEG).
Prevalence rate (PR) for active epilepsy was 6.54 /1000 population (95% confidence interval 5.48-7.60). Twenty-eight percent of the patients had partial seizures, 21% generalized seizures and in 51%, it was not possible to determine if the generalized seizures had focal onset or not. The epilepsy was symptomatic in 32% of the cases: pre or perinatal encephalopathy 23%, head injury 4%, childhood neurological infection 4% and stroke 1%. Febrile convulsions PR was 3.55 /1000 children under the age of 6 years and isolated seizures were documented in only 0.18 /1000 population.
The PR of epilepsy in Saudi Arabs is within the range of the values reported in most communities. The causes of symptomatic epilepsies revealed a predominance of perinatal and inherited factors. Isolated and non-convulsive seizures were probably under-recognized due to various social and cultural factors as well as to lack of sensitivity of the questionnaire for non-convulsive seizures.
确定沙特阿拉伯人群中癫痫及其他惊厥性疾病的患病率以及症状性癫痫的病因。
对居住在一个有限区域内的23700名沙特国民进行挨家挨户的调查。采用世界卫生组织（WHO）设计的用于检测神经系统疾病的方案作为筛查工具。所有疑似癫痫发作的患者均由神经科医生进行检查，92%的阳性病例接受了脑部计算机断层扫描（CT）和脑电图（EEG）检查。
活动性癫痫的患病率为6.54/1000人口（95%置信区间5.48 - 7.60）。28%的患者为部分性发作，21%为全身性发作，51%的患者无法确定全身性发作是否有局灶性起始。32%的病例中癫痫为症状性：产前或围产期脑病占23%，头部损伤占4%，儿童期神经系统感染占4%，中风占1%。6岁以下儿童热性惊厥的患病率为3.55/1000，孤立性发作仅记录为0.18/1000人口。
沙特阿拉伯人癫痫的患病率在大多数社区报告的范围内。症状性癫痫的病因显示围产期和遗传因素占主导。由于各种社会和文化因素以及问卷对非惊厥性发作缺乏敏感性，孤立性和非惊厥性发作可能未得到充分认识。
