Valentini V, Fabiani F, Perugini M, Vetrano S, Iannetti G
Department of Maxillofacial Surgery, University of Rome, La Sapienza, Italy.
J Craniofac Surg. 2001 Nov;12(6):565-8. doi: 10.1097/00001665-200111000-00013.
This paper presents a retrospective study carried out on a sample of 100 patients affected by pleomorphic adenoma of the parotid gland and treated at the Department of Maxillofacial Surgery at the University of Rome "La Sapienza" between January 1, 1989 and December 31, 1997. For the diagnosis of this neoformation, cytological tests were performed on material taken from the neoformation using fine needle aspiration and ultrasound scan. In some selected cases, a CT examination of the head and neck with medium contrast or Nuclear Magnetic Resonance (NMR) was carried out. This study sets out to examine the most suitable treatment to be followed for the removal of the pleomorphic adenoma of the parotid gland. In 56 cases the patients underwent a superficial, conservative parotidectomy. Forty one patients had a total parotidectomy with the facial nerve left intact and one patient had a total parotidectomy where the marginal mandibular nerve of the facial nerve was damaged. The remaining two patients involved in the study were suffering from a recurrent pleomorphic adenoma and in these two cases a total parotidectomy was performed where the facial nerve was killed. The removal of the cranial nerve VII in these patients proved necessary because the nerve fibers had adhered to the surrounding scar tissue of the tumor, either after previous surgery or due to repeated chronic phlogosis of the gland.
本文呈现了一项回顾性研究，该研究以100例腮腺多形性腺瘤患者为样本，这些患者于1989年1月1日至1997年12月31日在罗马第一大学“La Sapienza”颌面外科接受治疗。对于这种新生物的诊断，采用细针穿刺从新生物取材进行细胞学检查，并进行超声扫描。在一些选定的病例中，进行了中等对比度的头颈部CT检查或核磁共振（NMR）检查。本研究旨在探讨腮腺多形性腺瘤切除时最适合采用的治疗方法。56例患者接受了浅叶保守性腮腺切除术。41例患者进行了保留面神经的全腮腺切除术，1例患者进行全腮腺切除术时面神经下颌缘支受损。参与研究的其余2例患者患有复发性多形性腺瘤，这2例均进行了切除面神经的全腮腺切除术。在这些患者中切除颅神经VII被证明是必要的，因为神经纤维要么在先前手术后，要么由于腺体反复慢性炎症，已粘连到肿瘤周围的瘢痕组织上。
