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本文引用的文献

1
Etiology of Crohn's disease: the role of Mycobacterium avium paratuberculosis.克罗恩病的病因：副结核分枝杆菌的作用。
Trends Mol Med. 2001 Jun;7(6):247-52. doi: 10.1016/s1471-4914(01)01983-9.
2
Detection of Mycobacterium avium subspecies paratuberculosis in Crohn's diseased tissues by in situ hybridization.通过原位杂交检测克罗恩病组织中的副结核分枝杆菌鸟亚种。
Am J Gastroenterol. 2001 May;96(5):1529-35. doi: 10.1111/j.1572-0241.2001.03751.x.
3
Review article: Mycobacterium avium subsp. paratuberculosis as one cause of Crohn's disease.综述文章：副结核分枝杆菌作为克罗恩病的病因之一
Aliment Pharmacol Ther. 2001 Mar;15(3):337-46. doi: 10.1046/j.1365-2036.2001.00933.x.
4
Use of short-term culture for identification of Mycobacterium avium subsp. paratuberculosis in tissue from Crohn's disease patients.利用短期培养法鉴定克罗恩病患者组织中的副结核分枝杆菌亚种。
Clin Microbiol Infect. 2000 Jun;6(6):303-7. doi: 10.1046/j.1469-0691.2000.00093.x.
5
Looking for Mycobacterium paratuberculosis DNA by polymerase chain reaction (PCR) in orofacial granulomatosis (OFG) and oral Crohn's disease tissue in an Irish population.
Ir Med J. 2000 Oct;93(7):218.
6
In situ hybridization method for studies of cell wall deficient M. paratuberculosis in tissue samples.用于研究组织样本中细胞壁缺陷型副结核分枝杆菌的原位杂交方法。
Vet Microbiol. 2000 Dec 20;77(3-4):513-8. doi: 10.1016/s0378-1135(00)00336-9.
7
Results of multiple diagnostic tests for Mycobacterium avium subsp. paratuberculosis in patients with inflammatory bowel disease and in controls.炎症性肠病患者和对照组中鸟分枝杆菌副结核亚种的多项诊断测试结果。
J Clin Microbiol. 2000 Dec;38(12):4373-81. doi: 10.1128/JCM.38.12.4373-4381.2000.
8
Identification of cell wall deficient forms of M. avium subsp. paratuberculosis in paraffin embedded tissues from animals with Johne's disease by in situ hybridization.通过原位杂交在患有副结核病的动物石蜡包埋组织中鉴定副结核分枝杆菌细胞壁缺陷型。
J Microbiol Methods. 2000 Oct;42(2):185-95. doi: 10.1016/s0167-7012(00)00185-8.
9
Causation of Crohn's disease by Mycobacterium avium subspecies paratuberculosis.副结核分枝杆菌鸟亚种引发克罗恩病
Can J Gastroenterol. 2000 Jun;14(6):521-39. doi: 10.1155/2000/798305.
10
Isolation of Mycobacterium avium subsp paratuberculosis from breast milk of Crohn's disease patients.从克罗恩病患者母乳中分离出副结核分枝杆菌鸟型亚种。
Am J Gastroenterol. 2000 Apr;95(4):1094-5. doi: 10.1111/j.1572-0241.2000.01954.x.

通过原位杂交在克罗恩病患者活检标本中鉴定副结核分枝杆菌亚种。

Identification of Mycobacterium avium subsp. paratuberculosis in biopsy specimens from patients with Crohn's disease identified by in situ hybridization.

作者信息

Sechi L A, Mura M, Tanda F, Lissia A, Solinas A, Fadda G, Zanetti S

机构信息

Dipartimento di Scienze Biomediche, Sezione di Microbiologia Sperimentale e Clinica, Università degli studi di Sassari, 07100 Sassari, Italy.

出版信息

J Clin Microbiol. 2001 Dec;39(12):4514-7. doi: 10.1128/JCM.39.12.4514-4517.2001.

DOI:10.1128/JCM.39.12.4514-4517.2001
PMID:11724871
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC88575/
Abstract

Crohn's disease is a chronic inflammatory disease of the gastrointestinal tract of unknown etiology. We report on the presence of cell wall-deficient Mycobacterium avium subsp. paratuberculosis in 35 of 48 paraffin-embedded tissue specimens from 33 patients with Crohn's disease by in situ hybridization with IS900 as a probe.

摘要

克罗恩病是一种病因不明的胃肠道慢性炎症性疾病。我们通过以IS900为探针的原位杂交技术，在33例克罗恩病患者的48个石蜡包埋组织标本中的35个中发现了细胞壁缺陷型副结核分枝杆菌。