Truman James W, Riddiford Lynn M
Department of Zoology, University of Washington, Seattle, Washington 98195-1800, USA.
Annu Rev Entomol. 2002;47:467-500. doi: 10.1146/annurev.ento.47.091201.145230.
This review explores the roles of ecdysone and juvenile hormone (JH) in the evolution of complete metamorphosis and how metamorphosis, in turn, has impacted endocrine signaling. JH is a key player in the evolution of metamorphosis because it can act on embryos from more basal insect groups to suppress morphogenesis and cause premature differentiation, functions needed for transforming the transitional pronymphal stage of hemimetabolous insects into a functional larval stage. In the ancestral condition, imaginal-related growth is then delayed until JH finally disappears during the last larval instar. In the more derived groups of the Holometabola, selective tissues have escaped this JH suppression to form early-growing imaginal discs. We discuss how complete metamorphosis may have influenced the molecular aspects of both ecdysone and JH signaling.
本综述探讨了蜕皮激素和保幼激素（JH）在完全变态进化中的作用，以及变态如何反过来影响内分泌信号传导。JH是变态进化中的关键因素，因为它可以作用于更原始昆虫类群的胚胎，抑制形态发生并导致过早分化，这些功能是将不完全变态昆虫的过渡原蛹阶段转变为功能性幼虫阶段所必需的。在原始状态下，与成虫相关的生长会延迟，直到保幼激素在最后一龄幼虫期最终消失。在全变态昆虫的更多衍生类群中，选择性组织已摆脱这种保幼激素的抑制，形成早期生长的成虫盘。我们讨论了完全变态可能如何影响蜕皮激素和保幼激素信号传导的分子层面。
