Nkengfack A E, Azebaze A G, Waffo A K, Fomum Z T, Meyer M, van Heerden F R
Department of Organic Chemistry, Faculty of Science University of Yaounde I, PO Box 812 Yaounde, Cameroon.
Phytochemistry. 2001 Dec;58(7):1113-20. doi: 10.1016/s0031-9422(01)00368-5.
Bioassay-directed fractionation of the CH(2)Cl(2)-MeOH (1:1) extract of the stem bark of Erythrina indica, has resulted in the isolation of two new isoflavone derivatives named indicanines D and E together with 11 known compounds including: six isoflavones (genistein, wighteone, alpinumisoflavone, dimethylalpinumisoflavone, 8-prenyl erythrinin C, and erysenegalensein E), one cinnamate (erythrinassinate B), two pentacyclic triterpenes (oleanolic acid and erythrodiol), and two phytosterols (stigmasterol and its 3-O-beta-D-glucopyranoside). The structures of the new compounds were elucidated by means of spectroscopic analysis. The in vitro cytocidal activity against KB cells of some of the isolated compounds is also reported.
对刺桐茎皮的二氯甲烷-甲醇（1:1）提取物进行生物活性导向的分离，得到了两种新的异黄酮衍生物，命名为刺桐碱D和E，以及11种已知化合物，包括：六种异黄酮（染料木素、怀特酮、高山黄芩素、二甲基高山黄芩素、8-异戊烯基刺桐素C和刺桐塞内加尔素E）、一种肉桂酸酯（刺桐酸酯B）、两种五环三萜（齐墩果酸和刺桐二醇）和两种植物甾醇（豆甾醇及其3-O-β-D-葡萄糖苷）。通过光谱分析阐明了新化合物的结构。还报道了一些分离化合物对KB细胞的体外杀细胞活性。
