Perch M, Sodemann M, Jakobsen M S, Valentiner-Branth P, Steinsland H, Fischer T K, Lopes D D, Aaby P, Mølbak K
Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, Denmark.
Ann Trop Paediatr. 2001 Dec;21(4):313-8. doi: 10.1080/07430170120093490.
In community-based studies conducted from 1991 to 1997 in Guinea-Bissau, West Africa, stool specimens from children aged less than 5 years with diarrhoea were routinely examined for enteric parasites. Cryptosporidium parvum, found in 7.7% of 4,922 samples, was the second most common parasite, exceeded only by Giardia lamblia which was found in 14.8% of the samples. The highest prevalence of cryptosporidium was found in children aged 6-11 months, whereas the prevalence of other enteric parasites increased with age. Cryptosporidiosis showed a marked seasonal variation, with peak prevalences found consistently at the beginning of or just before the rainy seasons, May through July. By contrast, no seasonality was found for the enteric parasites Giardia lamblia or Entamoeba histolytica. We conclude that Cryptosporidium parvum is an important pathogen in children with diarrhoea.
1991年至1997年在西非几内亚比绍开展的社区研究中，对5岁以下腹泻儿童的粪便标本常规检测肠道寄生虫。在4922份样本中，7.7%检测出微小隐孢子虫，它是第二常见的寄生虫，仅次于蓝氏贾第鞭毛虫，后者在14.8%的样本中被发现。隐孢子虫在6至11个月大的儿童中患病率最高，而其他肠道寄生虫的患病率随年龄增长而增加。隐孢子虫病呈现明显的季节性变化，在5月至7月雨季开始时或即将开始前患病率始终达到峰值。相比之下，肠道寄生虫蓝氏贾第鞭毛虫或溶组织内阿米巴未发现季节性。我们得出结论，微小隐孢子虫是腹泻儿童的一种重要病原体。
