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[慢性阻塞性肺疾病(COPD)患者主观与客观健康测量指标之间的相关性]

[Correlation between subjective and objective health measurements in patients with chronic obstructive pulmonary disease (COPD)].

作者信息

Fernández Vargas A M, Bujalance Zafra M J, Leiva Fernández F, Martos Crespo F, García Ruiz A, Pradós Torres D

机构信息

Especialista en Medicina Familiar y Comunitaria. Unidad Docente de MFyC Málaga, Spain.

出版信息

Aten Primaria. 2001 Nov 30;28(9):579-87. doi: 10.1016/s0212-6567(01)70457-x.

Abstract

AIMS

Analyze the relation between objective health assessment (OHA) -Forced spirometry- and subjective health assessment (SHA) -quality of life- in patients with chronic obstructive pulmonary disease (COPD). Analyze the correlation between two different questionnaires to assess quality of life.

DESIGN

Cross-sectional study.

PARTICIPANTS

278 patients with COPD (confidence level 95%) from two urban health centers.

MAIN MEASUREMENTS

Personal interview.

VARIABLES

quality of life (Nottingham Health Profile; St George Respiratory Questionnaire); sociodemographic profile; diagnose of COPD; comorbidity; recent spirometry.

STATISTICAL ANALYSES

Descriptive statistics; test ji-squared, Kruskal-Wallis and the correlation coefficient.

RESULTS

Age: 66,9 years; sex: 88% male. Quality of life scales (mean and confidence intervals): Nottingham Health Profile subscales (total score 100 points): energy 40 (35.6-44.4), pain 35.9 (32.3-39.5), emotional reactions 32.5 (29.4-38.6), sleep 41.9 (37.8-45.9), social isolation 15.3 (12.7-17.9), mobility 36.7 (33.9-39.5) and global score 33.4 (30.8-36). St George Respiratory Questionnaire subscales (total scores 100 points): impact 38.01 (35.08-40.18), activity 53.8 (50.2-57.4), symptoms 37.7 (35.2-40.3) and global score 40.0 (38.6-43.2). The correlation coefficients between the two questionnaires ranged between 0.12 (for the sleep and symptoms dimensions: p = 0.03) and 0.66 (for the mobility and activity dimensions; p < 0.0001). There is a positive lineal relation between the two questionnaires and the spirometric stages of COPD (measured by the maximum respiratory volume in the first second).

CONCLUSIONS

We found a good correlation between the two quality of life questionnaires, but St George was more specific for respiratory illness. There is a mild-light correlation between objective and subjective health assessment in patients with COPD.

摘要

目的

分析慢性阻塞性肺疾病(COPD)患者的客观健康评估(OHA)——肺功能仪测定——与主观健康评估(SHA)——生活质量之间的关系。分析两种不同的生活质量调查问卷之间的相关性。

设计

横断面研究。

参与者

来自两个城市健康中心的278例COPD患者(置信水平95%)。

主要测量指标

个人访谈。

变量

生活质量(诺丁汉健康量表;圣乔治呼吸问卷);社会人口学资料;COPD诊断;合并症;近期肺功能测定。

统计分析

描述性统计;卡方检验、克鲁斯卡尔-沃利斯检验和相关系数。

结果

年龄:66.9岁;性别:88%为男性。生活质量量表(均值和置信区间):诺丁汉健康量表各维度(总分100分):精力40(35.6 - 44.4)、疼痛35.9(32.3 - 39.5)、情绪反应32.5(29.4 - 38.6)、睡眠41.9(37.8 - 45.9)、社会隔离15.3(12.7 - 17.9)、活动能力36.7(33.9 - 39.5)以及总体评分33.4(30.8 - 36)。圣乔治呼吸问卷各维度(总分100分):影响38.01(35.08 - 40.18)、活动53.8(50.2 - 57.4)、症状37.7(35.2 - 40.3)以及总体评分40.0(38.6 - 43.2)。两份问卷之间的相关系数在0.12(睡眠和症状维度:p = 0.03)至0.66(活动能力和活动维度;p < 0.0001)之间。两份问卷与COPD的肺功能分级(通过第一秒最大呼吸量测量)之间存在正线性关系。

结论

我们发现两份生活质量问卷之间具有良好的相关性,但圣乔治问卷对呼吸系统疾病更具特异性。COPD患者的客观和主观健康评估之间存在轻度至中度相关性。

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