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INDUCIBLE RESISTANCE TO ERYTHROMYCIN IN STAPHYLOCOCCUS AUREUS.金黄色葡萄球菌对红霉素的诱导抗性
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Diphtheroids of normal human skin.正常人皮肤的类白喉杆菌
Br J Dermatol. 1969;81:Suppl 1:47+. doi: 10.1111/j.1365-2133.1969.tb12833.x.
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Genetics of resistance to macrolide antibiotics and lincomycin in natural isolates of Streptococcus pyogenes.化脓性链球菌自然分离株对大环内酯类抗生素和林可霉素耐药性的遗传学研究
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Characterization of a plasmid determining resistance to erythromycin, lincomycin, and vernamycin Balpha in a strain Streptococcus pyogenes.化脓性链球菌菌株中一种决定对红霉素、林可霉素和维那霉素Bα耐药性的质粒的特性分析
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Inducible and constitutive resistance to macrolide antibiotics and lincomycin in clinically isolated strains of Streptococcus pyogenes.化脓性链球菌临床分离株对大环内酯类抗生素和林可霉素的诱导性及固有耐药性
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皮肤损伤处白喉棒状杆菌对红霉素和克林霉素的耐药性

Erythromycin and clindamycin resistance in Corynebacterium diphtheriae from skin lesions.

作者信息

Coyle M B, Minshew B H, Bland J A, Hsu P C

出版信息

Antimicrob Agents Chemother. 1979 Oct;16(4):525-7. doi: 10.1128/AAC.16.4.525.

DOI:10.1128/AAC.16.4.525
PMID:117748
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC352894/
Abstract

Erythromycin- and clindamycin-resistant Corynebacterium diphtheriae isolates were recovered from skin lesions. Resistance to erythromycin and clindamycin was induced by a subinhibitory concentration (0.03 microgram/ml) of erythromycin. Clindamycin (0.07 microgram/ml) was a more effective inducer of its own resistance than of erythromycin resistance. Erythromycin-inducible cross-resistance to vernamycin B alpha was demonstrated in disk diffusion tests.

摘要

从皮肤损伤处分离出了对红霉素和克林霉素耐药的白喉棒状杆菌菌株。亚抑菌浓度（0.03微克/毫升）的红霉素可诱导对红霉素和克林霉素的耐药性。克林霉素（0.07微克/毫升）对自身耐药性的诱导作用比对红霉素耐药性的诱导作用更有效。在纸片扩散试验中证实了红霉素诱导的对维纳霉素Bα的交叉耐药性。