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柚皮苷和芦丁类黄酮的降胆固醇作用

[Hypocholesterolemic effect of naringin and rutin flavonoids].

作者信息

da Silva R R, de Oliveira T T, Nagem T J, Pinto A S, Albino L F, de Almeida M R, de Moraes G H, Pinto J G

机构信息

Universidade Federal de Viçosa, Minas Gerais, Brazil.

出版信息

Arch Latinoam Nutr. 2001 Sep;51(3):258-64.

PMID:11795241
Abstract

Flavonoids are pigments fenolics of plants that possess several biological activities, and many of these are associated with prevention of chronic diseases as cancer and hyperlipidemia. This work had as objective evaluates the effect of the flavonoids naringin and rutin on the metabolism lipidic of chicks hypercholesterolemic. In agreement with the results it can be observed that naringin and rutin reduced the levels of total cholesterol significantly, cholesterol-LDL, cholesterol-VLDL and triglycerols, not presenting, however, reductions in the levels of cholesterol-HDL.

摘要

黄酮类化合物是植物中的酚类色素,具有多种生物活性,其中许多与预防癌症和高脂血症等慢性疾病有关。这项工作的目的是评估柚皮苷和芦丁对高胆固醇血症雏鸡脂质代谢的影响。根据结果可以观察到,柚皮苷和芦丁显著降低了总胆固醇、低密度脂蛋白胆固醇、极低密度脂蛋白胆固醇和甘油三酯的水平,然而,高密度脂蛋白胆固醇水平没有降低。

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