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人工椎间盘置换:未来趋势?

Prosthetic disc replacement: the future?

作者信息

Bao Qi-Bin, Yuan Hansen A

机构信息

Disc Dynamics, Inc., Minnetonka, MN 55345, USA.

出版信息

Clin Orthop Relat Res. 2002 Jan(394):139-45. doi: 10.1097/00003086-200201000-00016.

Abstract

Since it first was introduced more than 90 years ago, disc arthrodesis remains the main surgical method for the treatment of degenerative disc disease. Although this procedure does relatively well in stabilizing the anterior column and relieving low back pain by eliminating motion, it is not physiologic and it alters the stress distribution on the adjacent segments. Although the issue of whether this stress alteration leads to symptomatic degeneration remains debatable, it probably is agreed that disc arthrodesis is not the best choice for correcting or preventing anterior column instability caused by degenerative disc disease. The ultimate solution for reestablishing anterior column stability is to restore not only the anatomy but also the normal mechanical function by using a more functional device, prosthetic disc replacement. During the past 401 years, many different designs have been attempted for prosthetic disc replacement. Many biomechanical studies have shown that normal mechanical functions of a disc can be restored by a disc prosthesis. Some early clinical studies have shown promising results. Although it might take more effort to optimize the design and reduce costs and risks, prosthetic disc replacement will be the future of spine care.

摘要

自90多年前首次引入以来,椎间盘融合术仍然是治疗退行性椎间盘疾病的主要手术方法。尽管该手术在稳定前柱和通过消除运动来缓解腰痛方面表现相对良好,但它不符合生理状态,并且会改变相邻节段的应力分布。尽管这种应力改变是否会导致症状性退变仍存在争议,但人们可能普遍认为,椎间盘融合术并非纠正或预防由退行性椎间盘疾病引起的前柱不稳定的最佳选择。重建前柱稳定性的最终解决方案是通过使用更具功能性的装置——人工椎间盘置换术,不仅恢复解剖结构,还恢复正常的力学功能。在过去的401年里,人们尝试了许多不同的人工椎间盘置换设计。许多生物力学研究表明,椎间盘假体可以恢复椎间盘的正常力学功能。一些早期临床研究已显示出有希望的结果。尽管优化设计、降低成本和风险可能需要付出更多努力,但人工椎间盘置换术将成为脊柱治疗的未来发展方向。

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