Jampel H D
Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Trans Am Ophthalmol Soc. 2001;99:301-17.
To determine how glaucoma patients with various degrees of vision loss rate their vision, and to determine if the Esterman binocular visual field test and other visual function tests correlate with those ratings.
Two hundred thirty-seven glaucoma patients evaluated their vision using 2 utility tests, the linear rating scale and the time trade-off test, and 2 quality-of-life instruments, the National Eye Institute Visual Function Questionnaire (VFQ) and the Short Form 36 (SF-36). Their results were compared to clinical tests of their vision and to persons with normal vision (n = 12) and blind persons (n = 12).
On a scale of 0 (blind) to 100 (ideal), subjects with normal vision rated their vision higher (90 +/- 8.0) than did glaucoma subjects and suspects (75.7 +/- 17.6) and "blind" subjects (15.6 +/- 15.3), P = .001. Mean scores for the Esterman test were 89.7 +/- 13.4 for the glaucoma group. The Esterman test correlated moderately with the overall VFQ score (partial correlation coefficient [PCC] = 0.32, P = .001), but only weakly with the linear rating scale (PCC = 0.17, P = .02) and the time trade-off test (PCC = -0.16, P = .06). Correlation between the linear rating scale and the overall VFQ score was good (PCC = 0.56, P = .0001) and was moderate with several domains of the SF-36 (e.g., social function PCC = 0.32, P = .0001).
Utility values that glaucoma patients assign to their vision do not correlate well with Esterman test results. A challenge for the future will be designing clinical tests that better correlate with patient perceptions.
确定不同视力丧失程度的青光眼患者如何评价自己的视力,并确定埃斯特曼双眼视野测试及其他视觉功能测试与这些评价之间是否存在相关性。
237名青光眼患者使用两种效用测试(线性评分量表和时间权衡测试)以及两种生活质量评估工具(美国国立眼科研究所视觉功能问卷[VFQ]和简明健康调查问卷[SF-36])对自己的视力进行评价。将他们的结果与视力临床测试结果进行比较,并与视力正常者(n = 12)和盲人(n = 12)进行比较。
在从0(失明)到100(理想)的评分范围内,视力正常的受试者对自己视力的评分(90±8.0)高于青光眼患者和疑似青光眼患者(75.7±17.6)以及“失明”受试者(15.6±15.3),P = 0.001。青光眼组埃斯特曼测试的平均得分为89.7±13.4。埃斯特曼测试与VFQ总分呈中度相关(偏相关系数[PCC] = 0.32,P = 0.001),但与线性评分量表(PCC = 0.17,P = 0.02)和时间权衡测试(PCC = -0.16,P = 0.06)的相关性较弱。线性评分量表与VFQ总分的相关性良好(PCC = 0.56,P = 0.0001),与SF-36的几个领域呈中度相关(例如,社会功能PCC = 0.32,P = 0.0001)。
青光眼患者赋予其视力的效用值与埃斯特曼测试结果的相关性不佳。未来的一项挑战将是设计出与患者认知更具相关性的临床测试。