Odds F C
Department of Bacteriology & Mycology, Janssen Research Foundation, B-2340 Beerse, Belgium.
Acta Stomatol Belg. 1997 Jun;94(2):75-80.
Candida species are responsible for all but exceptional examples of oral fungal infection. Oral Candida lesions are seen only in patients who are predisposed to such disease by physiological or immunological abnormalities, particularly by extremes of age and HIV infections. The infections can be acute or chronic, pseudomembranous ("thrush") or atrophic (erythemateous). In the AIDS patient, mixtures of clinical types may be seen. Diagnosis of oral Candida infection requires microscopic or culture proof of the involvement of a Candida species. Treatment depends on the type of patient and the type of infection. Topical antifungal agents, usually of the imidazole, triazole or polyene type, are commonly used, although non-specific antiseptics are recommended for denture cleansing in cases of denture-associated stomatitis.
除极少数例外情况外，念珠菌属是口腔真菌感染的主要致病菌。口腔念珠菌病仅见于因生理或免疫异常，特别是年龄极端情况和艾滋病毒感染而易患此类疾病的患者。感染可为急性或慢性，假膜性（“鹅口疮”）或萎缩性（红斑性）。在艾滋病患者中，可能会出现多种临床类型的混合。口腔念珠菌感染的诊断需要通过显微镜检查或培养证明有念珠菌属的感染。治疗取决于患者类型和感染类型。通常使用局部抗真菌剂，通常为咪唑类、三唑类或多烯类，不过对于义齿性口炎病例，推荐使用非特异性防腐剂进行义齿清洁。
