Klis F M, de Groot P, Hellingwerf K
Swammerdam Institute for Life Sciences, University of Amsterdam, The Netherlands.
Med Mycol. 2001;39 Suppl 1:1-8.
We have recently presented a molecular model of the cell wall of Saccharomyces cerevisiae. Here we discuss the evidence that a similar model is also valid for Candida albicans. We further discuss how cell-wall proteins are linked to the skeletal layer of the wall, and their potential functions. We emphasize that the composition and structure of the cell wall depends on growth conditions. Finally, cell-wall damage seems to activate a salvage mechanism resulting in restructuring of the cell wall.
我们最近提出了酿酒酵母细胞壁的分子模型。在此，我们讨论有证据表明类似模型对白色念珠菌同样适用。我们还进一步讨论了细胞壁蛋白如何与细胞壁的骨架层相连以及它们的潜在功能。我们强调细胞壁的组成和结构取决于生长条件。最后，细胞壁损伤似乎会激活一种补救机制，从而导致细胞壁的重塑。
