杆菌肽和锰离子对产生菌地衣芽孢杆菌的影响。

The effect of bacitracin and Mn(II)ions upon the producer strain Bacillus licheniformis.

作者信息

Haavik H I

出版信息

Acta Pathol Microbiol Scand B. 1975 Oct;83(5):513-8. doi: 10.1111/j.1699-0463.1975.tb00132.x.

DOI:10.1111/j.1699-0463.1975.tb00132.x

Abstract

The peptide antibiotic bacitracin is inhibitory to growth of the producer strain Bacillus licheniformis only in the presence of excess manganese(II)ions. Both the early and the late growth are inhibited in a similar manner upon addition of bacitracin and manganese(II)ions. Thus, B. licheniformis does not develop resistance to its own antibiotic during growth. Added bacitracin is stimulatory to growth of B. licheniformis in media with a very low content of manganese(II)ions. These results support the hypothesis that bacitracin participates in the manganese transport of the producer strain B. licheniformis.

摘要

肽抗生素杆菌肽仅在存在过量锰（II）离子的情况下，才会抑制其产生菌地衣芽孢杆菌的生长。添加杆菌肽和锰（II）离子后，早期和晚期生长均以类似方式受到抑制。因此，地衣芽孢杆菌在生长过程中不会对自身抗生素产生抗性。在锰（II）离子含量极低的培养基中，添加的杆菌肽对地衣芽孢杆菌的生长具有刺激作用。这些结果支持了杆菌肽参与产生菌地衣芽孢杆菌的锰转运这一假说。