关于杆菌肽肽在地衣芽孢杆菌微量金属转运中的作用

On the role of bacitracin peptides in trace metal transport by Bacillus licheniformis.

作者信息

Haavik H I

出版信息

J Gen Microbiol. 1976 Oct;96(2):393-9. doi: 10.1099/00221287-96-2-393.

Abstract

Bacitracin markedly increased the toxic effect of several divalent metal ions towards growth of the producer strain Bacillus licheniformis ATCCI4580. Magnesium ions antagonized the toxic effect of these divalent cations both in the presence and absence of bacitracin. It is suggested that bacitracin increases the uptake of several divalent metal ions. The function of the bacitracin peptides may be to extract essential divalent cations from 'waiting sites' on the surface of the cells and transfer the cations to the transport mechanisms in the cytoplasmic membrane.

摘要

杆菌肽显著增强了几种二价金属离子对其产生菌地衣芽孢杆菌ATCC14580生长的毒性作用。在有和没有杆菌肽存在的情况下，镁离子均能拮抗这些二价阳离子的毒性作用。有人提出，杆菌肽会增加几种二价金属离子的摄取。杆菌肽肽的功能可能是从细胞表面的“等待位点”提取必需的二价阳离子，并将这些阳离子转移至细胞质膜中的转运机制。