Frölich Michael A, Caton Donald
Department of Anesthesiology, University of Florida College of Medicine, Gainesville, Florida 32610, USA.
Can J Anaesth. 2002 Feb;49(2):185-9. doi: 10.1007/BF03020493.
Hypotension is the most frequent complication of spinal anesthesia in pregnant patients. This study was designed to identify patients at risk for postspinal hypotension based on preoperative vital signs before and after an orthostatic challenge.
Forty healthy women scheduled for elective Cesarean section were enrolled in this prospective trial. Blood pressure (BP) and heart rate (HR) were recorded with the patient in the lateral supine position and after standing up. After a bupivacaine spinal anesthetic, BP was obtained every two minutes for 30 min. Ephedrine treatment was administered based on the degree of hypotension observed. Hemodynamic parameters were correlated to ephedrine requirements (Spearman's rank order correlation).
There was a significant correlation in baseline maternal HR and ephedrine requirements (P=0.005). The degree of orthostatic changes in mean arterial BP and HR did not correlate with postspinal hypotension.
Baseline HR may be predictive of obstetric spinal hypotension. Higher baseline HR, possibly reflecting a higher sympathetic tone, may be a useful parameter to predict postspinal hypotension.
低血压是孕妇脊髓麻醉最常见的并发症。本研究旨在根据术前体位改变前后的生命体征,确定脊髓麻醉后发生低血压的高危患者。
40例计划行择期剖宫产的健康女性纳入本前瞻性试验。记录患者侧卧位及站立后的血压(BP)和心率(HR)。布比卡因脊髓麻醉后,每两分钟测一次血压,共测30分钟。根据观察到的低血压程度给予麻黄碱治疗。血流动力学参数与麻黄碱需求量相关(Spearman等级相关)。
产妇基线心率与麻黄碱需求量存在显著相关性(P = 0.005)。平均动脉压和心率的体位改变程度与脊髓麻醉后低血压无关。
基线心率可能是产科脊髓麻醉后低血压的预测指标。较高的基线心率可能反映较高的交感神经张力,可能是预测脊髓麻醉后低血压的有用参数。