Seo Dong Bum, Lee Seoung Woo, Song Joon Ho, Lee Kyong Joo, Han Jee Young, Kim Moon Jae
Division of Nephrology and Hypertension, Department of Internal Medicine, Inha University College of Medicine, Inchon, Korea.
Yonsei Med J. 2002 Feb;43(1):114-8. doi: 10.3349/ymj.2002.43.1.114.
In systemic lupus erythematosus (SLE), acute renal failure (ARF) is usually associated with severe lupus nephritis and ARF associated with other glomerular diseases is extremely rare. We recently encountered a patient with ARF that was associated with a minimal change nephrotic syndrome (MCNS) in SLE. A 41-year-old woman presented with a nephrotic syndrome and ARF. She fulfilled four of the American College of Rheumatology criteria for the classification of SLE. However, a renal biopsy revealed that there were no glomerular abnormalities and no deposition of immune complex. The generalized edema disappeared and the high creatinine levels decreased after prednisolone therapy.
在系统性红斑狼疮（SLE）中，急性肾衰竭（ARF）通常与严重的狼疮性肾炎相关，而与其他肾小球疾病相关的ARF极为罕见。我们最近遇到一名患有ARF的患者，该患者的ARF与SLE中的微小病变肾病综合征（MCNS）相关。一名41岁女性出现肾病综合征和ARF。她符合美国风湿病学会SLE分类标准中的四条。然而，肾活检显示没有肾小球异常，也没有免疫复合物沉积。泼尼松龙治疗后，全身水肿消失，高肌酐水平下降。
