Hansebout R R, Kuchner E F, Romero-Sierra C
Surg Neurol. 1975 Dec;4(6):531-6.
Canine spinal cords were compressed by a cylindrical balloon placed in the T-13 epidural space and maintained at 160 mm Hg for one hour. Fifteen minutes after deflation, either local hypothermia or parenteral dexamethasone therapy was initiated. Local hypothermia (dorsal dura mater at 6 degrees C for four hours) was achieved with a miniature epidural heat exchanger which kept cooling fluid isolated from tissue. At seven weeks, the treated groups achieved motor ratings which were significantly superior to those of the untreated group. The untreated group were unable to walk, while both treated groups were able to do so.
将圆柱形球囊置于T-13硬膜外间隙对犬脊髓进行压迫，并维持在160毫米汞柱1小时。放气15分钟后，开始局部低温治疗或胃肠外给予地塞米松治疗。局部低温治疗（硬脊膜背侧温度为6摄氏度，持续4小时）通过微型硬膜外热交换器实现，该热交换器使冷却液与组织隔离。7周时，治疗组的运动评分显著高于未治疗组。未治疗组无法行走，而两个治疗组均能够行走。
