Cabrera H A, Drake M A
Am J Clin Pathol. 1975 Nov;64(5):700-4. doi: 10.1093/ajcp/64.5.700.
Five patients in a coronary care unit were involved in an epidemic caused by a nonfermenting Gram-negative bacillus, presumptively identified by our laboratory as Pseudomonas cepacia. All medications administered intravenously to these patients were cultured. Because morphine was the only such medication common to the treatment of all the patients involved, a vial used in the unit at that time was cultured, as were two previously-entered vials of saline solution and several sterile vials of distilled water used in the preparation of injectable medication. The Pseudomonas cepacia organism was recovered from one of the vials of saline solution. The epidemic ended as soon as the practice of re-entering the vials of sterile saline solution was discontinued.
冠心病监护病房的五名患者感染了一种由非发酵革兰氏阴性杆菌引起的传染病,我们实验室初步鉴定为洋葱伯克霍尔德菌。对这些患者静脉注射的所有药物都进行了培养。由于吗啡是所有相关患者治疗中唯一共同使用的此类药物,因此当时该病房使用的一个小瓶进行了培养,之前开封的两瓶盐溶液以及用于配制注射用药物的几个无菌蒸馏水小瓶也进行了培养。从一瓶盐溶液中分离出了洋葱伯克霍尔德菌。一旦停止重复使用无菌盐溶液小瓶的做法,疫情就结束了。