Icks A, Haastert B, Enck P, Rathmann W, Giani G
Dept. of Biometrics & Epidemiology, German Diabetes Research Institute, Düsseldorf, Germany.
Z Gastroenterol. 2002 Mar;40(3):177-83. doi: 10.1055/s-2002-22324.
There are few population-based studies on prevalence of functional bowel disorders (FBD) and related health care seeking. The aim of the present study was to evaluate the prevalence of FBD in a population-based sample and to assess FBD-related health care seeking and medication in Germany.
Cross-sectional study, based on an age- and sex-stratified random sample of 2,400 subjects aged 21-80 years in Düsseldorf, Germany (about 500,000 population). Assessment was performed using a postal written questionnaire.
Prevalence of gastrointestinal pain or discomfort in the past 12 months was assessed, in particular, lower abdominal pain and irritable bowel syndrome (IBS). Furthermore, health care seeking and medication (prescribed and over-the-counter) due to FBD was assessed. Multiple logistic regression (survey estimated) was performed to evaluate associations of FBD with age, sex, and the socioeconomic status (SES).
1,281 subjects (53.4 %) were analyzed. Standardized prevalences were 22.6 % (95 %-CI: 20.3 - 25.1 %) for lower abdominal pain and 12.5 % (10.7-14.5 %) for IBS. Both lower abdominal pain and IBS were significantly less frequent in the older population compared to younger subjects. No significant differences were found for gender and SES. Among subjects with lower abdominal pain and IBS, 55.1 % and 49.3 % reported health care seeking due to their GI disorders, and 63.9 % and 56.2 % reported use of medication, respectively.
A high prevalence of functional bowel disorders was found in this population-based study in Germany. Only about half of the subjects reported health care seeking due to their bowel disorders. Self-medication with over-the-counter agents was frequently performed.
关于功能性肠病（FBD）患病率及相关医疗保健寻求情况的基于人群的研究较少。本研究的目的是评估基于人群样本中FBD的患病率，并评估德国与FBD相关的医疗保健寻求情况及用药情况。
横断面研究，基于德国杜塞尔多夫2400名年龄在21 - 80岁的受试者（约50万人口）按年龄和性别分层的随机样本。通过邮寄书面问卷进行评估。
评估过去12个月胃肠道疼痛或不适的患病率，特别是下腹痛和肠易激综合征（IBS）。此外，评估因FBD而进行的医疗保健寻求及用药情况（处方药和非处方药）。采用多重逻辑回归（调查估计）来评估FBD与年龄、性别和社会经济地位（SES）之间的关联。
对1281名受试者（53.4%）进行了分析。下腹痛的标准化患病率为22.6%（95%可信区间：20.3 - 25.1%），IBS为12.5%（10.7 - 14.5%）。与年轻受试者相比，老年人群中下腹痛和IBS的发生率均显著较低。性别和SES方面未发现显著差异。在下腹痛和IBS患者中，分别有55.1%和49.3%的人报告因胃肠道疾病寻求医疗保健，分别有63.9%和56.2%的人报告使用了药物。
在德国这项基于人群的研究中发现功能性肠病的患病率很高。只有约一半的受试者报告因肠道疾病寻求医疗保健。非处方药的自我用药情况很常见。
