新型细菌聚酮合酶起始单元的生物合成与连接
Biosynthesis and attachment of novel bacterial polyketide synthase starter units.
作者信息
Moore Bradley S, Hertweck Christian
机构信息
Division of Medicinal Chemistry, College of Pharmacy, University of Arizona, Tucson 85721-0207, USA.
出版信息
Nat Prod Rep. 2002 Feb;19(1):70-99. doi: 10.1039/b003939j.
DOI:10.1039/b003939j
PMID:11902441
Abstract
The biosynthesis and mode of attachment of a wide range of polyketide synthase (PKS) starter units in bacteria are covered in this review. Natural, unnatural, and engineered starter units associated with type I and type II PKSs are reported. The literature through early 2001 is reviewed, and 240 references cited.
摘要
本综述涵盖了细菌中多种聚酮合酶（PKS）起始单元的生物合成及连接方式。报道了与I型和II型PKS相关的天然、非天然及工程化起始单元。对截至2001年初的文献进行了综述，并引用了240篇参考文献。
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