Roach V J, Cheung T F, Chung T K, Hjelm N M, Waring M A, Loong E P, Haines C J
Departments of Obstetrics and Gynecology, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong.
Climacteric. 1998 Dec;1(4):290-5. doi: 10.3109/13697139809085557.
The aims of this study were to estimate the dietary intake of phytoestrogens and to measure urinary phytoestrogen excretion in postmenopausal Chinese women.
Postmenopausal Chinese women were recruited from the hormone replacement clinic of the Prince of Wales Hospital. Dietary intake of phytoestrogen-rich foods was estimated using a food frequency questionnaire. Urinary output of the isoflavonoids daidzein and genistein and the metabolite of daidzein, equol, was measured using high-performance liquid chromatography.
The mean daily excretion of daidzein, genistein and equol was 3.24 (+/- 3.63), 1.47 (+/- 1.75) and 0.64 (+/- 1.53) mumol, respectively. The total mean daily isoflavonoid excretion was 5.36 (+/- 5.27) mumol.
Urinary excretion of isoflavonoid phytoestrogens in this Chinese population was lower than that reported in Japanese subjects. This may be due to the higher consumption of legumes, especially soy products, in the Japanese compared to the Chinese diet. The intake of green vegetables was higher in the Chinese subjects, and this food group may be the main contributor to their total phytoestrogen intake.
本研究旨在评估绝经后中国女性的植物雌激素膳食摄入量，并测定其尿中植物雌激素的排泄量。
从威尔士亲王医院激素替代诊所招募绝经后中国女性。使用食物频率问卷评估富含植物雌激素食物的膳食摄入量。采用高效液相色谱法测定异黄酮大豆苷元、染料木黄酮及其代谢产物大豆苷元雌马酚的尿排泄量。
大豆苷元、染料木黄酮和雌马酚的平均每日排泄量分别为3.24（±3.63）、1.47（±1.75）和0.64（±1.53）μmol。异黄酮的总平均每日排泄量为5.36（±5.27）μmol。
该中国人群中异黄酮类植物雌激素的尿排泄量低于日本受试者的报告值。这可能是由于与中国饮食相比，日本人食用豆类尤其是豆制品的量更高。中国受试者的绿色蔬菜摄入量较高，该食物组可能是其植物雌激素总摄入量的主要贡献者。
