Anjaneyulu Ammanamanchi S R, Rao Vadali Lakshmana, Sreedhar Karanam
School of Chemistry, Andhra University, Visakhapatnam-530 003, India.
J Nat Prod. 2002 Mar;65(3):382-5. doi: 10.1021/np010262u.
The roots of Excoecaria agallocha yielded four new diterpenoids, ent-3 beta,20-epoxy-3 alpha,6 alpha-dihydroxykaur-16-ene (agallochin F) (1), 3beta,20-epoxy-3 alpha-hydroxybeyer-15-ene (agallochin G) (2), 3 beta,20:15R,16S-diepoxy-3 alpha-beyeranol (agallochin H) (3), and 3 beta,20-epoxy-3 alpha,6 alpha-dihydroxy-18-nor-beyer-15-ene (agallochin I) (4), along with three known derivatives, 2-acetoxy-1,15-beyeradiene-3,12-dione (5), 2-hydroxy-1,15-beyeradiene-3,12-dione (6), and ent-kauran-16 beta-ol-3-one. The structures of 1-4 were determined by spectroscopic (NMR and MS) data interpretation.
海漆的根产生了四种新的二萜类化合物，对映-3β,20-环氧-3α,6α-二羟基贝壳杉-16-烯（海漆素F）（1）、3β,20-环氧-3α-羟基贝叶烷-15-烯（海漆素G）（2）、3β,20:15R,16S-二环氧-3α-贝叶烷醇（海漆素H）（3）和3β,20-环氧-3α,6α-二羟基-18-降-贝叶烷-15-烯（海漆素I）（4），以及三种已知衍生物，2-乙酰氧基-1,15-贝叶二烯-3,12-二酮（5）、2-羟基-1,15-贝叶二烯-3,12-二酮（6）和对映-贝壳杉-16β-醇-3-酮。通过光谱（NMR和MS）数据解析确定了1-4的结构。
