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The basal ganglia and disorders of movement: pathophysiological mechanisms.

作者信息

Obeso José A, Rodríguez-Oroz María C, Rodríguez Manuel, Arbizu Javier, Giménez-Amaya José M

机构信息

Department of Neurology, Clinica Universitaria and Medical School, University of Navarra, Pamplona 31008, Spain.

出版信息

News Physiol Sci. 2002 Apr;17:51-5. doi: 10.1152/nips.01363.2001.

Abstract

The basal ganglia are part of a neuronal network organized in parallel circuits. The "motor circuit" is most relevant to the pathophysiology of movement. Abnormal increment or reduction in the inhibitory output activity of basal ganglia give rise, respectively, to poverty and slowness of movement (i.e., Parkinson's disease) or dyskinesias.

摘要

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