Roengsumran Sophon, Musikul Kusalin, Petsom Amorn, Vilaivan Tirayut, Sangvanich Polkit, Pornpakakul Surachai, Puthong Songchan, Chaichantipyuth Chaiyo, Jaiboon Nongnuj, Chaichit Narongsak
Planta Med. 2002 Mar;68(3):274-7. doi: 10.1055/s-2002-23138.
A new furoclerodane, croblongifolin, together with one known clerodane, crovatin and one known labdane, nidorellol, were isolated from the stem bark of Croton oblongifolius. Structures were established based on spectroscopic and X-ray analysis. Croblongifolin showed a significant cytotoxicity against various human tumor cell lines including HEP-G2, SW620, CHAGO, KATO3 and BT474.
从长叶巴豆的茎皮中分离出一种新的克罗烷型二萜类化合物——长叶巴豆克罗烷醇，以及一种已知的克罗烷型二萜类化合物——克罗瓦亭和一种已知的半日花烷型二萜类化合物——尼多瑞醇。通过光谱分析和X射线分析确定了其结构。长叶巴豆克罗烷醇对包括HEP-G2、SW620、CHAGO、KATO3和BT474在内的多种人类肿瘤细胞系显示出显著的细胞毒性。
