来自长叶巴豆茎皮的呋喃二萜类化合物。

Furanocembranoids from the stem bark of Croton oblongifolius.

作者信息

Pudhom Khanitha, Vilaivan Tirayut, Ngamrojanavanich Nattaya, Dechangvipart Suchon, Sommit Damrong, Petsom Amorn, Roengsumran Sophon

机构信息

Research Centre for Bioorganic Chemistry, Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.

出版信息

J Nat Prod. 2007 Apr;70(4):659-61. doi: 10.1021/np060520t. Epub 2007 Mar 7.

DOI:10.1021/np060520t

PMID:17341114

Abstract

Four novel furanocembranoids (1-4) were isolated from the stem bark of Croton oblongifolius. Their structures were elucidated on the basis of spectroscopic analysis, mainly NMR and MS. Compounds 1, 3, and 4 exhibited good cytotoxicity against several human tumor cell lines.

摘要

从长圆叶巴豆的茎皮中分离出四种新型呋喃贝壳杉烷类化合物（1-4）。基于光谱分析，主要是核磁共振（NMR）和质谱（MS）对其结构进行了阐明。化合物1、3和4对几种人类肿瘤细胞系表现出良好的细胞毒性。