Woo K
Mount Sinai Hospital, Toronto, Ontario, Canada.
Can J Nurs Res. 2000 Dec;32(3):85-98.
A cross-sectional design was used to examine the mediating effect of physical activity between dyspnea and fatigue in patients with chronic obstructive pulmonary disease (COPD). Dyspnea was measured using a vertical visual analogue scale, fatigue using the Profile of Mood States-Fatigue subscale, and physical activity using the 6-minute-walk (6MW) test. A convenience sample of 17 male and 22 female patients with COPD provided data for analysis. The sample was characterized by relatively high forced expiratory volume in 1 second (FEV1) of predicted normal values, indicating mild lung impairment and high mean levels of fatigue and dyspnea. Controlling for age and FEV1, dyspnea, physical activity, and fatigue were significantly interrelated. Results of the regression analysis suggested the mediating function of physical activity between dyspnea and fatigue. Limitations and suggestions for practice and future research are presented.
采用横断面设计来检验慢性阻塞性肺疾病（COPD）患者中身体活动在呼吸困难与疲劳之间的中介作用。使用垂直视觉模拟量表测量呼吸困难，使用情绪状态量表-疲劳分量表测量疲劳，使用6分钟步行（6MW）测试测量身体活动。17名男性和22名女性COPD患者的便利样本提供了分析数据。该样本的特征是1秒用力呼气量（FEV1）相对于预测正常值较高，表明肺部轻度受损，且疲劳和呼吸困难的平均水平较高。在控制年龄和FEV1后，呼吸困难、身体活动和疲劳之间存在显著的相互关系。回归分析结果表明身体活动在呼吸困难与疲劳之间起中介作用。文中还提出了局限性以及对实践和未来研究的建议。
