Kerdpanich A, Watanaveeradej V, Samakoses R, Chumnanvanakij S, Chulyamitporn T, Sumeksri P, Vuthiwong C, Kounruang C, Nisalak A, Endy T
Pediatric Department, Phramongkutklao Hospital, Bangkok, Thailand.
Southeast Asian J Trop Med Public Health. 2001 Sep;32(3):488-93.
We report a case of vertical transmission of dengue infection in an infant. The mother's was a term pregnancy with a history of chronic hypertension. She presented with high fever of 3 days duration 5 days prior to delivery. Her initial complete blood count showed platelet count of 64,000/mm3. Dengue hemorrhagic fever was diagnosed 2 days later and symptomatic treatment was given. During labor her platelets dropped to 11,000/mm3 and platelet concentrate was given. Cesarean section was performed due to prolonged second stage of labor. Her infant was normal at birth except for petechiae on the left thigh. The child's platelet count was 34,000/mm3 and low grade fever was detected on the first day. Clinical sepsis was suspected and antibiotic treatment was started and continued for 4 days until all the cultures came back as negative. Both mother and her baby made an uneventful recovery and were discharged 6 days after delivery with normal platelet counts. Maternal blood was positive for IgM antibody to dengue virus. Both cord blood and the baby's blood were positive for dengue virus serotype 2 by PCR.
我们报告了一例婴儿登革热感染垂直传播的病例。母亲足月妊娠，有慢性高血压病史。她在分娩前5天出现持续3天的高热。她最初的全血细胞计数显示血小板计数为64,000/mm³。2天后诊断为登革出血热并给予对症治疗。分娩期间她的血小板降至11,000/mm³，并输注了血小板浓缩液。由于第二产程延长，进行了剖宫产。她的婴儿出生时正常，只是左大腿有瘀点。孩子的血小板计数为34,000/mm³，第一天检测到低热。怀疑有临床败血症，开始使用抗生素治疗并持续4天，直到所有培养结果均为阴性。母亲和她的宝宝恢复顺利，分娩后6天血小板计数正常出院。母亲血液中登革病毒IgM抗体呈阳性。脐带血和婴儿血液经PCR检测登革病毒2型均呈阳性。
