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某些药物在水溶液中的氯化钠当量、冰点降低特性及溶血作用。III:补充值。

Sodium chloride equivalents, cryoscopic properties, and hemolytic effects of certain medicinals in aqueous solution. III: Supplemental values.

作者信息

Sapp C, Lord M, Hammarlund E R

出版信息

J Pharm Sci. 1975 Nov;64(11):1884-6. doi: 10.1002/jps.2600641132.

Abstract

A supplemental table of sodium chloride equivalents and freezing-point depressions at various concentrations for 44 different substances in aqueous solution is presented. Also given in the table is the isosmotic concentration of each material that can form such a solution. The degree of hemolysis of human erythrocytes was determined in 24 different isosmotic solutions, and the data are presented in a table to supplement the previously pub lished values. Eleven isosmotic solutions prevented hemolysis, and 13 others failed to prevent hemolysis.

摘要

本文给出了44种不同物质在水溶液中不同浓度下的氯化钠当量和冰点降低值的补充表格。表格中还给出了每种能够形成此类溶液的物质的等渗浓度。测定了24种不同等渗溶液中人红细胞的溶血程度,相关数据列于表格中,以补充先前发表的值。11种等渗溶液可防止溶血,另外13种则不能防止溶血。

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