一株实验室衍生的、对氨苄西林高度耐药的鼠伤寒沙门氏菌菌株的特性分析，该菌株导致一名婴儿患脑膜炎。
Characterization of a laboratory-derived, high-level ampicillin-resistant Salmonella enterica serovar Typhimurium strain that caused meningitis in an infant.
作者信息
Chiu Cheng-Hsun, Chu Chishih, Su Lin-Hui, Wu Wan-Yu, Wu Tsu-Lan
机构信息
Department of Pediatrics, Chang Gung Children's Hospital, Kweishan 333, Taoyuan, Taiwan.
出版信息
Antimicrob Agents Chemother. 2002 May;46(5):1604-6. doi: 10.1128/AAC.46.5.1604-1606.2002.
Abstract
A Salmonella enterica serovar Typhimurium strain that harbored a plasmid carrying a TEM-1-type beta-lactamase gene was isolated from the blood and cerebrospinal fluid of an infant with meningitis. This 3.2-kb plasmid was further characterized to be a nonconjugative pGEM series cloning vector containing a foreign insert. The strain was likely laboratory derived and contaminated the environment before it caused the infection.
摘要
从一名患脑膜炎婴儿的血液和脑脊液中分离出一株携带含有TEM-1型β-内酰胺酶基因质粒的肠炎沙门氏菌鼠伤寒血清型菌株。这个3.2kb的质粒经进一步鉴定为一个含有外源插入片段的非接合型pGEM系列克隆载体。该菌株很可能来源于实验室，在引起感染之前污染了环境。
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