黑腹果蝇中的遗传不稳定性：MR元件诱导2号染色体特定缺失
Genetic instability in Drosophila melanogaster: the induction of specific chromosome 2 deletions by MR elements.
作者信息
Green M M, Shepherd S H
出版信息
Genetics. 1979 Jul;92(3):823-32. doi: 10.1093/genetics/92.3.823.
Abstract
We describe the spontaneous induction of deletions by MR elements at the l(2)gl, net, pr and cn loci. The frequent induction of l(2)gl deletions mimics the high frequency of l(2)gl alleles found in wild populations of D. melanogaster. We suggest that these and other data that we present militate for the conclusion that, in the wild, autonomous MR elements occur and function as mutators. We contend that MR elements are not simply the by-products of hybridization between wild and laboratory strains.
摘要
我们描述了MR元件在l(2)gl、net、pr和cn基因座处自发诱导缺失的情况。l(2)gl缺失的频繁诱导类似于在黑腹果蝇野生种群中发现的l(2)gl等位基因的高频率。我们认为，我们所呈现的这些以及其他数据都支持这样一个结论：在野外，自主的MR元件作为诱变剂存在并发挥作用。我们认为MR元件并非仅仅是野生菌株和实验室菌株杂交的副产物。
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