Dietzsch H J, Rupprecht E, Wunderlich P
Padiatr Padol. 1975;10(2):176-83.
After establishing a suitable definition of chronic and relapsing bronchitis in childhood in the G.D.R. in 1969 corresponding epidemiologic studies carried out in school beginners and school children in Dresden revealed a prevalence rate of 1,64% to 3,06% for this disease. The analysis of bronchologic examinations of 274 children performed at the Pediatric Clinic of the Medical Academy Dresden during the last four years showed a deforming bronchitis as the most frequent finding in the bronchogram of 51% of the patients. Malformations of the tracheobronchial tree could be demonstrated in 16% of the children examined. The frequency of bronchiectases was at a very low level (9%) and showed a regression by the half as compared with former results. The results of bacteriological examinations of the bronchial secretion, quantitative analyses of the immune globulins in the serum and the bronchial secretion and the alpha-1-antitrypsin are discussed as causative factors for chronic and relapsing bronchitis in childhood. For assessing the prognosis of deforming bronchitis 220 children had a bronchologic follow-up examination in four bronchologic centers for children in the G.D.R. after a one or several years' dispensary treatment. An improvement or a normalisation of the findings could be demonstrated by means of the bronchogram in 62% of these patients, whereas a deterioration or a transition to bronchiectases was observed in only 22% of the patients.
1969年,在民主德国确立了儿童慢性复发性支气管炎的合适定义后,在德累斯顿对刚入学儿童和在校学生进行的相应流行病学研究显示,该疾病的患病率为1.64%至3.06%。德累斯顿医学院儿科诊所对过去四年中274名儿童进行的支气管检查分析表明,在51%患者的支气管造影中,变形性支气管炎是最常见的发现。在16%接受检查的儿童中可发现气管支气管树畸形。支气管扩张的发生率非常低(9%),与以前的结果相比下降了一半。讨论了支气管分泌物的细菌学检查结果、血清和支气管分泌物中免疫球蛋白的定量分析以及α-1-抗胰蛋白酶作为儿童慢性复发性支气管炎病因的情况。为评估变形性支气管炎的预后,在民主德国的四个儿童支气管病中心,对220名儿童在接受了一年或数年的门诊治疗后进行了支气管病随访检查。通过支气管造影可证明,这些患者中有62%的检查结果有所改善或恢复正常,而只有22%的患者出现病情恶化或转变为支气管扩张。