Fukuda Misao, Fukuda Kiyomi, Shimizu Takashi, Andersen Claus Yding, Byskov Anne Grete
Fukuda Ladies Clinic, 30-9 Kariya, Ako, 678-0239, Hyogo, Japan.
Lancet. 2002 Apr 20;359(9315):1407-8. doi: 10.1016/S0140-6736(02)08362-9.
We assessed whether the smoking habits of parents around the time of conception affects the likelihood of the offspring being male or female. We found that the offspring sex ratio (male to female) was lower when either one or both of the parents smoked more than 20 cigarettes per day compared with couples in which neither of the parents smoked. We found the lowest sex ratio among children whose mothers and fathers both smoked more than 20 cigarettes per day (p<0.0001). Parental periconceptional smoking might be a contributing factor to a lower male to female sex ratio of offspring.
我们评估了受孕前后父母的吸烟习惯是否会影响后代为男性或女性的可能性。我们发现，与父母均不吸烟的夫妇相比，父母一方或双方每天吸烟超过20支时，后代的性别比（男比女）更低。我们发现，父母双方每天吸烟均超过20支的孩子的性别比最低（p<0.0001）。受孕前后父母吸烟可能是导致后代男女性别比降低的一个因素。
