Moretti F, Uberti-Foppa C, Quiros-Roldan E, Fanti L, Lillo F, Lazzarin A
Institute of Infectious and Tropical Diseases, University of Brescia, 25123 Brescia, Italy.
J Clin Pathol. 2002 May;55(5):397-8. doi: 10.1136/jcp.55.5.397.
Human herpesvirus oesophagitis in human immunodeficiency virus positive patients is caused by cytomegalovirus and herpes simplex virus; no cases of oesophagitis and oesophagobrochial fistula as a result of varicella zoster virus (VZV) have been reported to date. This report describes the case of a patient with a 2-3 mm deep oesophageal ulcer whose viral culture was positive for VZV. The patient was treated with acyclovir with resolution of the symptomatology. After the end of the induction treatment, because of the onset of fever and fits of coughing during eating, the patient underwent oesophagography, which showed an ulcer with an oesophagobronchial fistula in the middle and lower third of the oesophagus. This case report stresses the role of VZV infection as a possible cause of oesophagobronchial fistula, a rare but benign condition in patients with AIDS.
人类免疫缺陷病毒阳性患者的人疱疹病毒性食管炎由巨细胞病毒和单纯疱疹病毒引起；迄今为止，尚无因水痘带状疱疹病毒（VZV）导致食管炎和食管支气管瘘的病例报告。本报告描述了一名患有2 - 3毫米深食管溃疡的患者，其病毒培养VZV呈阳性。该患者接受阿昔洛韦治疗后症状缓解。诱导治疗结束后，由于患者进食时出现发热和咳嗽发作，遂进行食管造影，结果显示食管中下段有一个伴有食管支气管瘘的溃疡。本病例报告强调了VZV感染作为食管支气管瘘可能病因的作用，食管支气管瘘在艾滋病患者中虽罕见但为良性病症。
