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猪肠道病毒II组和III组的测序揭示了这两个病毒组的独特特征。

Sequencing of porcine enterovirus groups II and III reveals unique features of both virus groups.

作者信息

Krumbholz Andi, Dauber Malte, Henke Andreas, Birch-Hirschfeld Eckhard, Knowles Nick J, Stelzner Axel, Zell Roland

机构信息

Institut für Virologie, Klinikum der Friedrich-Schiller-Universität, 07745 Jena, Germany.

出版信息

J Virol. 2002 Jun;76(11):5813-21. doi: 10.1128/jvi.76.11.5813-5821.2002.

DOI:10.1128/jvi.76.11.5813-5821.2002
PMID:11992011
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC137026/
Abstract

The molecular classification of the porcine enterovirus (PEV) groups II and III was investigated. The sequence of the almost complete PEV-8 (group II) genome reveals that this virus has unique L and 2A gene regions. A reclassification of this group into a new picornavirus genus is suggested. PEV group III viruses are typical enteroviruses. They differ from other enteroviruses by a prolonged stem-loop D of the 5'-cloverleaf structure.

摘要

对猪肠道病毒（PEV）II组和III组进行了分子分类研究。几乎完整的PEV - 8（II组）基因组序列显示，该病毒具有独特的L基因和2A基因区域。建议将该组重新分类为一个新的小RNA病毒属。PEV III组病毒是典型的肠道病毒。它们与其他肠道病毒的区别在于5'-三叶草结构的茎环D延长。

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本文引用的文献

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J Virol. 2002 Feb;76(3):1244-51. doi: 10.1128/jvi.76.3.1244-1251.2002.
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J Gen Virol. 2001 Feb;82(Pt 2):417-424. doi: 10.1099/0022-1317-82-2-417.
3
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J Virol. 2001 Feb;75(4):1620-31. doi: 10.1128/JVI.75.4.1620-1631.2001.
4
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5
The 2A proteins of three diverse picornaviruses are related to each other and to the H-rev107 family of proteins involved in the control of cell proliferation.三种不同微小核糖核酸病毒的2A蛋白彼此相关，且与参与细胞增殖调控的H-rev107蛋白家族相关。
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