Köhnlein T, Welte T, Tan L B, Elliott M W
Otto-von-Guericke-Universität Magdeburg, Department for Pulmonary and Intensive Care Medicine, Germany.
Thorax. 2002 Jun;57(6):547-54. doi: 10.1136/thorax.57.6.547.
The prevalence, prognosis, clinical presentation, pathophysiology, diagnosis, and treatment of the central sleep apnoea syndrome (CSAS) are reviewed and its relationship with congestive heart failure (CHF) is discussed. Adequately powered trials are needed with survival and health status as end points to establish whether correction of sleep related breathing abnormalities improves the outcome in patients with CHF.
本文综述了中枢性睡眠呼吸暂停综合征（CSAS）的患病率、预后、临床表现、病理生理学、诊断和治疗，并讨论了其与充血性心力衰竭（CHF）的关系。需要进行以生存和健康状况为终点的充分有力的试验，以确定纠正与睡眠相关的呼吸异常是否能改善CHF患者的预后。
