Howell Amy B
Marucci Center for Blueberry and Cranberry Research and Extension, Rutgers, The State University of New Jersey, Chatsworth 08019, USA.
Crit Rev Food Sci Nutr. 2002;42(3 Suppl):273-8. doi: 10.1080/10408390209351915.
One of the major health benefits attributed to the ingestion of cranberry juice is the maintenance of urinary tract health. Traditionally, the juice was thought to cause acidification of the urine resulting in a bacteriostatic effect. However, recent research has demonstrated that a bacterial antiadhesion mechanism is responsible. Proanthocyanidins with unique molecular structures have been isolated from cranberry fruit that exhibit potent bacterial antiadhesion activity. Little is known about the bioavailability and structure-activity relationships of cranberry proanthocyanidins. Data on how certain structural features of the molecules can influence bioactivity and bioavailability are reviewed.
摄入蔓越莓汁对健康的主要益处之一是维持尿路健康。传统上，人们认为这种果汁会使尿液酸化，从而产生抑菌作用。然而，最近的研究表明，其作用机制是细菌抗黏附。已从蔓越莓果实中分离出具有独特分子结构的原花青素，这些原花青素具有强大的细菌抗黏附活性。关于蔓越莓原花青素的生物利用度和构效关系，人们了解甚少。本文综述了有关分子的某些结构特征如何影响生物活性和生物利用度的数据。
