螫刺昆虫过敏：毒液IgE抗体的检测及临床意义

Stinging insect allergy: detection and clinical significance of venom IgE antibodies.

作者信息

Reisman R E, Wypych J, Arbesman C E

出版信息

J Allergy Clin Immunol. 1975 Dec;56(6):443-9. doi: 10.1016/0091-6749(75)90062-7.

PMID:1206184

Abstract

Venom-specific IgE antibodies in 109 sera from patients who had had immediate systemic allergic reactions following insect stings were measured by the radioallergosorbent (RAST) procedure. The majority of sera contained IgE antibodies to either bee, yellow jacket, or hornet venoms. Some sera had positive RAST reactions with 2 or 3 venoms, but others contained single venom-specific IgE antibodies. Of 24 patients who had large local reactions, the sera of 12 contained venom IgE antibodies. The RAST procedure provides an accurate means of documenting IgE-mediated allergic sensitivity to stinging insects.

摘要

采用放射变应原吸附试验（RAST）检测了109例昆虫叮咬后发生速发型全身过敏反应患者血清中的毒液特异性IgE抗体。大多数血清含有针对蜜蜂、黄胡蜂或大黄蜂毒液的IgE抗体。一些血清对2种或3种毒液有阳性RAST反应，但其他血清含有单一毒液特异性IgE抗体。在24例发生严重局部反应的患者中，12例患者的血清含有毒液IgE抗体。RAST试验为记录IgE介导的对蜇刺昆虫的过敏敏感性提供了一种准确的方法。