Bányai Krisztián, Angyal Márta, Körmendi Eva, Lakatos Ferenc, Uj Mária, Szücs György
Regionális Virológiai Laboratóríum, Allami Népegészségügyi és Tisztiorvosi Szolgálat Baranya Megyei Intézete, Pécs.
Orv Hetil. 2002 Jun 2;143(22):1347-52.
Group A rotaviruses are known as the major cause of severe dehydrating diarrhoea in infants.
In adults, the rotavirus infections are usually asymptomatic. In the present study the authors report a group A rotavirus outbreak in a psychiatric nursing home for adults.
The outbreak lasted 3 weeks; the attack rate was 20%. The mean age of patients was 39 y (range 21 to 65; n = 25). The symptoms were mild, and most of the patients recovered within 2 or 3 days. The epidemiological data suggested that the virus was introduced by a patient, and it was transmitted by person-to-person route. Rotavirus positive specimens were characterised by serotyping and electropherotyping. The serotype-specific monoclonal antibody immunoassay demonstrated the circulation of a common strain with G1 specificity. These samples shared identical genome profile with strains circulated in the paediatric communities of the country.
In Hungary, this is the first published gastroenteritis outbreak among adults caused by group A rotaviruses with G1 serotype specificity.
A组轮状病毒是婴儿严重脱水腹泻的主要病因。
在成人中，轮状病毒感染通常无症状。在本研究中，作者报告了一起发生在成人精神病疗养院的A组轮状病毒暴发。
暴发持续了3周；罹患率为20%。患者的平均年龄为39岁（范围21至65岁；n = 25）。症状较轻，大多数患者在2或3天内康复。流行病学数据表明，病毒由一名患者传入，并通过人际传播途径传播。通过血清分型和电泳分型对轮状病毒阳性标本进行了特征分析。血清型特异性单克隆抗体免疫测定表明，一种具有G1特异性的常见毒株在传播。这些样本与该国儿科社区中传播的毒株具有相同的基因组图谱。
在匈牙利，这是首次发表的由具有G1血清型特异性的A组轮状病毒引起的成人胃肠炎暴发。
