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用于治疗类风湿性关节炎的电刺激

Electrical stimulation for the treatment of rheumatoid arthritis.

作者信息

Brosseau L U, Pelland L U, Casimiro L Y, Robinson V I, Tugwell P E, Wells G E

机构信息

School of Rehabilitation Sciences, University of Ottawa, Department of Rehabilitation Sciences, 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5.

出版信息

Cochrane Database Syst Rev. 2002;2002(2):CD003687. doi: 10.1002/14651858.CD003687.


DOI:10.1002/14651858.CD003687
PMID:12076504
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8725644/
Abstract

BACKGROUND: Electrical stimulation is one of several rehabilitation interventions suggested for the management of rheumatoid arthritis (RA) to enhance muscle performance. OBJECTIVES: To assess the effectiveness of electrical stimulation for improving muscle strength and function in clients with RA. SEARCH STRATEGY: We searched MEDLINE, Embase, Healthstar, Sports Discus, CINAHL, the Cochrane Controlled Trials Register, the PEDro database, the specialized registry of the Cochrane musculoskeletal group and the Cochrane field of physical and related therapies up to January 2002 according to the sensitive search strategy for RCTs designed for the Cochrane Collaboration. The search was complemented with handsearching of the reference lists. Key experts in the area were contacted for further articles. SELECTION CRITERIA: All randomized controlled trials (RCTs) and controlled clinical trials (CCTs), case-control and cohort studies comparing ES against placebo or another active intervention in patients with RA were selected, according to an a priori protocol. No language restrictions were applied. DATA COLLECTION AND ANALYSIS: Two independent reviewers determined the studies to be included based on a priori inclusion criteria. Data were independently abstracted by the same two reviewers, and checked by a third reviewer using a pre-developed form. The same two reviewers, using a validated scale, independently assessed the methodological quality of the RCTs and CCTs. The data analysis was performed using Peto Odds ratios. MAIN RESULTS: Of the two relevant studies that were identified in the literature, only one RCT met the inclusion criteria. This RCT compared the effects of two electrostimulation (ES) protocols on hand function in general and on the performance of the first dorsal interosseous muscle in particular, in 15 patients with RA and secondary disuse atrophy of the first dorsal interosseous of the dominant hand. The results showed that ES had significant benefit when compared to a control no treatment group in terms of muscle strength and fatigue resistance of the first dorsal interosseous. Most favourable results were obtained by using a patterned stimulation derived from a fatigued motor unit of the first dorsal interosseous in a normal hand rather than a fixed 10 Hz stimulation frequency. Side effects of the ES application were not reported. REVIEWER'S CONCLUSIONS: ES was shown to have a clinically beneficial effect on grip strength and fatigue resistance for RA patients with muscle atrophy of the hand. However, these conclusions are limited by the low methodological quality of the trial included. More well-designed studies are therefore needed to provide further evidence of the benefits of ES in the management of RA.

摘要

背景:电刺激是为类风湿关节炎(RA)管理而建议的几种康复干预措施之一,以增强肌肉性能。 目的:评估电刺激对改善RA患者肌肉力量和功能的有效性。 检索策略:根据为Cochrane协作网设计的RCT敏感检索策略,我们检索了截至2002年1月的MEDLINE、Embase、Healthstar、Sports Discus、CINAHL、Cochrane对照试验注册库、PEDro数据库、Cochrane肌肉骨骼组专门注册库以及物理和相关疗法的Cochrane领域。通过手工检索参考文献列表对检索进行补充。联系该领域的关键专家获取更多文章。 选择标准:根据预先制定的方案,选择所有比较电刺激(ES)与安慰剂或另一种积极干预措施的类风湿关节炎患者的随机对照试验(RCT)、对照临床试验(CCT)、病例对照研究和队列研究。不设语言限制。 数据收集与分析:两名独立的评审员根据预先设定的纳入标准确定纳入的研究。数据由同两名评审员独立提取,并由第三名评审员使用预先制定的表格进行核对。同两名评审员使用经过验证的量表独立评估RCT和CCT的方法学质量。使用Peto比值比进行数据分析。 主要结果:在文献中确定的两项相关研究中,只有一项RCT符合纳入标准。该RCT比较了两种电刺激(ES)方案对15例患有RA且优势手第一背侧骨间肌继发性废用性萎缩患者的总体手部功能,特别是第一背侧骨间肌性能的影响。结果表明,与无治疗的对照组相比,ES在第一背侧骨间肌的肌肉力量和抗疲劳能力方面具有显著益处。通过使用来自正常手部第一背侧骨间肌疲劳运动单位的模式刺激而非固定的10Hz刺激频率,获得了最有利的结果。未报告ES应用的副作用。 评审员结论:对于手部肌肉萎缩的RA患者,ES对手部握力和抗疲劳能力具有临床有益效果。然而,这些结论受到纳入试验方法学质量较低的限制。因此,需要更多设计良好的研究来提供ES在RA管理中益处的进一步证据。

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引用本文的文献

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Efficacy and safety of electrical stimulation for functional impairment and pain in patients with rheumatoid arthritis: a protocol for systematic review and network meta-analysis of RCTs.

BMJ Open. 2025-4-9

[2]
A reconfigurable integrated smart device for real-time monitoring and synergistic treatment of rheumatoid arthritis.

Sci Adv. 2024-5-3

[3]
Non-pharmacological treatment in difficult-to-treat rheumatoid arthritis.

Front Med (Lausanne). 2022-8-29

[4]
Does TENS Reduce the Intensity of Acute and Chronic Pain? A Comprehensive Appraisal of the Characteristics and Outcomes of 169 Reviews and 49 Meta-Analyses.

Medicina (Kaunas). 2021-10-4

[5]
A systematic review exploring the evidence reported to underpin exercise dose in clinical trials of rheumatoid arthritis.

Rheumatology (Oxford). 2020-11-1

[6]
Radiographic Analysis of Simulated First Dorsal Interosseous and Opponens Pollicis Loading Upon Thumb CMC Joint Subluxation: A Cadaver Study.

Hand (N Y). 2018-1

[7]
Complementary and Alternative Medicine Use in Rheumatoid Arthritis: Considerations for the Pharmacological Management of Elderly Patients.

Drugs Aging. 2017-4

[8]
Non-pharmacological interventions for fatigue in rheumatoid arthritis.

Cochrane Database Syst Rev. 2013-8-23

[9]
What Does the Cochrane Collaboration Say about Rheumatoid Arthritis?

Physiother Can. 2012

[10]
Translating Policy into Practice for Community-Based Management of Rheumatoid Arthritis: Targeting Professional Development Needs among Physiotherapists.

Int J Rheumatol. 2012

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