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[乙酰胆碱对金鱼视网膜水平细胞膜电位及青蛙视网膜电图的影响]

[The effect of acetylcholine on the membrane potential of goldfish retina horizontal cells and the frog electroretinogram].

作者信息

Zak P P, Lelekova T V

出版信息

Neirofiziologiia. 1975;7(1):55-9.

PMID:1207795
Abstract

The effect of acetylcholine was studied as applied to horizontal cells of the goldfish retina and frog electroretinogram ACh (1-10-9--1-10-3 M) depolarized the cells. The highest level of depolarization never reached the O-level of the membrane potential and was approximately equal to the membrane potential in the dark. ACh (1-10-2--5-10-2 M) inhibited b- and d-waves and revealed the stable PIII component. It is supposed that ACh may be a transmitter in retinal outer synpatic layer.

摘要

研究了乙酰胆碱作用于金鱼视网膜水平细胞及青蛙视网膜电图的效果。乙酰胆碱(1×10⁻⁹ ~ 1×10⁻³ M)使细胞去极化。去极化的最高水平从未达到膜电位的零水平,且大致等于暗环境下的膜电位。乙酰胆碱(1×10⁻² ~ 5×10⁻² M)抑制b波和d波,并显示出稳定的PIII成分。据推测,乙酰胆碱可能是视网膜外突触层的一种神经递质。

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