Evans J R, Fletcher A E, Wormald R P L, Ng E Siu-Woon, Stirling S, Smeeth L, Breeze E, Bulpitt C J, Nunes M, Jones D, Tulloch A
Department of Epidemiology and International Eye Health, Institute of Ophthalmology, London, UK.
Br J Ophthalmol. 2002 Jul;86(7):795-800. doi: 10.1136/bjo.86.7.795.
To measure the prevalence of visual impairment in a large representative sample of people aged 75 years and over participating in the MRC trial of assessment and management of older people in the community.
53 practices in the MRC general practice research framework. Data were obtained from 14 600 participants aged 75 years and older. Prevalence of visual impairment overall (binocular visual acuity <6/18) which was categorised separately into low vision (binocular visual acuity <6/18-3/60) or blindness (binocular visual acuity of <3/60). The prevalence of binocular acuity <6/12 was presented for comparison with other studies. Visual acuity was measured using Glasgow acuity charts; glasses, if worn, were not removed.
Visual acuity was available for 14 600 people out of 21 241 invited (69%). Among people with visual acuity data, 12.4% overall (1803) were visually impaired (95% confidence intervals 10.8% to 13.9%); 1501 (10.3%) were categorised as having low vision (8.7% to 11.8%), and 302 (2.1%) were blind (1.8% to 2.4%). At ages 75-79, 6.2% of the cohort were visually impaired (5.1% to 7.3%) with 36.9% at age 90+ (32.5% to 41.3%). At ages 75-79, 0.6% (0.4% to 0.8%) of the study population were blind, with 6.9% (4.8% to 9.0%) at age 90+. In multivariate regression, controlling for age, women had significant excess risk of visual impairment (odds ratio 1.43, 95% confidence interval 1.29 to 1.58). Overall, 19.9% of study participants had a binocular acuity of less than 6/12 (17.8% to 22.0%).
The results from this large study show that visual impairment is common in the older population and that this risk increases rapidly with advancing age, especially for women. A relatively conservative measure of visual impairment was used. If visual impairment had been defined as visual acuity of <6/12 (American definition of visual impairment), the age specific prevalence estimates would have increased by 60%.
在参与社区老年人评估与管理医学研究委员会(MRC)试验的75岁及以上具有广泛代表性的人群样本中,测量视力损害的患病率。
MRC全科医学研究框架中的53家医疗机构。数据来自14600名75岁及以上的参与者。总体视力损害(双眼视力<6/18)的患病率被分别分类为低视力(双眼视力<6/18 - 3/60)或失明(双眼视力<3/60)。呈现双眼视力<6/12的患病率以与其他研究进行比较。使用格拉斯哥视力表测量视力;若佩戴眼镜,则不摘下。
在21241名受邀者中,14600人的视力数据可用(69%)。在有视力数据的人群中,总体12.4%(1803人)存在视力损害(95%置信区间10.8%至13.9%);1501人(10.3%)被分类为低视力(8.7%至11.8%),302人(2.1%)失明(1.8%至2.4%)。在75 - 79岁年龄段,该队列中6.2%的人存在视力损害(5.1%至7.3%),90岁及以上者为36.9%(32.5%至41.3%)。在75 - 79岁年龄段,研究人群中0.6%(0.4%至0.8%)失明,90岁及以上者为6.9%(4.8%至9.0%)。在多变量回归分析中,控制年龄因素后,女性视力损害风险显著更高(比值比1.43,95%置信区间1.29至1.58)。总体而言,19.9%的研究参与者双眼视力低于6/12(17.8%至22.0%)。
这项大型研究的结果表明,视力损害在老年人群中很常见,且这种风险随年龄增长迅速增加,尤其是女性。本研究采用了相对保守的视力损害衡量标准。如果将视力损害定义为视力<6/12(美国视力损害定义),特定年龄的患病率估计将增加60%。