Hamidou Mohamed A, Fradet Gerard, Kadi Anne-Marie, Robin Anne, Moreau Anne, Magnaval Jean-François
Department of Internal Medicine, Centre Hospitalier Universitaire Hotel-Dieu, Nantes, France.
Arch Intern Med. 2002 Jul 8;162(13):1521-4. doi: 10.1001/archinte.162.13.1521.
Vasculitis associated with helminthic infection is rare. We report a case of systemic negative antineutrophil cytoplasmic antibodies vasculitis associated with Toxocara canis infection documented by enzyme-linked immunosorbent assay and Western blot analysis. This case report is unusual because of lymphocytic temporal arteritis and renal involvement. The spontaneous remission of systemic vasculitis without use of steroids or immunosuppressive agents favors a close relationship between vasculitis and the parasite that is more than a coincidental association. To our knowledge, this is the first observation of temporal vasculitis associated with helminthic infection, extending the clinical spectrum of visceral larva migrans.
与蠕虫感染相关的血管炎较为罕见。我们报告一例经酶联免疫吸附测定和蛋白质印迹分析证实的与犬弓首蛔虫感染相关的系统性抗中性粒细胞胞浆抗体阴性血管炎。该病例报告不同寻常之处在于存在淋巴细胞性颞动脉炎和肾脏受累情况。系统性血管炎在未使用类固醇或免疫抑制剂的情况下自发缓解，这表明血管炎与寄生虫之间存在密切关系，而非仅仅是巧合。据我们所知，这是首次观察到与蠕虫感染相关的颞动脉炎，扩展了内脏幼虫移行症的临床谱。
