须癣毛癣菌诱导人表皮角质形成细胞产生白细胞介素-8和肿瘤坏死因子α
Interleukin-8 and tumor necrosis factor alpha production in human epidermal keratinocytes induced by Trichophyton mentagrophytes.
作者信息
Nakamura Yuka, Kano Rui, Hasegawa Atsuhiko, Watanabe Shinichi
机构信息
Department of Dermatology, Teikyo University School of Medicine, Tokyo, Japan.
出版信息
Clin Diagn Lab Immunol. 2002 Jul;9(4):935-7. doi: 10.1128/cdli.9.4.935-937.2002.
Abstract
Production of interleukin-8 (IL-8) and tumor necrosis factor alpha (TNF-alpha) was confirmed by enzyme-linked immunosorbent assay in a medium where human epidermal keratinocytes were cocultured with Trichophyton mentagrophytes for 1 to 12 h. IL-8 and TNF-alpha mRNAs were also detected in the keratinocytes cocultured with T. mentagrophytes.
摘要
通过酶联免疫吸附测定法证实，在人表皮角质形成细胞与须癣毛癣菌共培养1至12小时的培养基中产生了白细胞介素-8（IL-8）和肿瘤坏死因子α（TNF-α）。在与须癣毛癣菌共培养的角质形成细胞中也检测到了IL-8和TNF-α的信使核糖核酸。
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