嗜热绿硫菌TLS的全基因组序列，一种光合、厌氧的绿色硫细菌。
The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium.
作者信息
Eisen Jonathan A, Nelson Karen E, Paulsen Ian T, Heidelberg John F, Wu Martin, Dodson Robert J, Deboy Robert, Gwinn Michelle L, Nelson William C, Haft Daniel H, Hickey Erin K, Peterson Jeremy D, Durkin A Scott, Kolonay James L, Yang Fan, Holt Ingeborg, Umayam Lowell A, Mason Tanya, Brenner Michael, Shea Terrance P, Parksey Debbie, Nierman William C, Feldblyum Tamara V, Hansen Cheryl L, Craven M Brook, Radune Diana, Vamathevan Jessica, Khouri Hoda, White Owen, Gruber Tanja M, Ketchum Karen A, Venter J Craig, Tettelin Hervé, Bryant Donald A, Fraser Claire M
机构信息
The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
出版信息
Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9509-14. doi: 10.1073/pnas.132181499. Epub 2002 Jul 1.
The complete genome of the green-sulfur eubacterium Chlorobium tepidum TLS was determined to be a single circular chromosome of 2,154,946 bp. This represents the first genome sequence from the phylum Chlorobia, whose members perform anoxygenic photosynthesis by the reductive tricarboxylic acid cycle. Genome comparisons have identified genes in C. tepidum that are highly conserved among photosynthetic species. Many of these have no assigned function and may play novel roles in photosynthesis or photobiology. Phylogenomic analysis reveals likely duplications of genes involved in biosynthetic pathways for photosynthesis and the metabolism of sulfur and nitrogen as well as strong similarities between metabolic processes in C. tepidum and many Archaeal species.
嗜温绿硫真细菌嗜热栖热菌（Chlorobium tepidum）TLS的完整基因组被确定为一条由2,154,946个碱基对组成的单环染色体。这代表了绿菌门（Chlorobia）的首个基因组序列，该门成员通过还原性三羧酸循环进行不产氧光合作用。基因组比较已在嗜热栖热菌中鉴定出在光合物种中高度保守的基因。其中许多基因尚未明确功能，可能在光合作用或光生物学中发挥新作用。系统基因组分析揭示了参与光合作用以及硫和氮代谢的生物合成途径中基因可能存在的重复，以及嗜热栖热菌与许多古菌物种代谢过程之间的强烈相似性。
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