van't Riet M, de Vos van Steenwijk P J, Kleinrensink G J, Steyerberg E W, Bonjer H J
Department of General Surgery, Erasmus University Medical Centre Rotterdam-Dijkzigt, Rotterdam, The Netherlands.
Surg Endosc. 2002 Dec;16(12):1713-6. doi: 10.1007/s00464-001-9202-7. Epub 2002 Jul 8.
Fixation of the mesh is crucial for the successful laparoscopic repair of incisional hernias. In the present experimental study, we used a pig model to compare the tensile strengths of mesh fixation with helical titanium coils (tackers) and transabdominal wall sutures.
Thirty-six full-thickness specimens (5 x 7 cm) of the anterior abdominal wall of nine pig cadavers were randomized for fixation of a polypropylene mesh (7 x 7 cm) by either tackers or transabdominal wall sutures. The number of fixation points varied from one to five per 7-cm tissue length, with distances between fixation points of 2.3, 1.8, 1.4, and 1.2 cm, respectively. The force required to disrupt the mesh fixation (tensile strength) was measured by a dynamometer. Statistical analysis was performed using the Wilcoxon test and the Spearman rank correlation test.
The mean tensile strength of mesh fixation by transabdominal sutures was significantly greater than that by tackers for each number of fixation points: 67 N vs 28 N for a single fixation point (p <0.001), 115 N vs 42 N for two fixation points (p <0.001), 150 N vs 63 N for three fixation points (p <0.05), 151 N vs 73 N for four fixation points (p <0.05), and 150 N vs 82 N for five fixation points (p <0.05). Increasing the number of fixation points over three per 7 cm (distance between fixation points of 1.8 cm) did not improve tensile strength.
The tensile strength of transabdominal sutures is up to 2.5 times greater than the tensile strength of tackers. Therefore, the use of transabdominal sutures for mesh fixation appears to be preferable for laparoscopic incisional hernia repair.
网片固定对于腹腔镜切口疝修补术的成功至关重要。在本实验研究中,我们使用猪模型比较螺旋钛线圈(钉合器)和经腹壁缝合固定网片的拉伸强度。
将9头猪尸体的36个腹壁全层标本(5×7 cm)随机分为用钉合器或经腹壁缝合固定聚丙烯网片(7×7 cm)。每7 cm组织长度的固定点数量从1个到5个不等,固定点之间的距离分别为2.3 cm、1.8 cm、1.4 cm和1.2 cm。用测力计测量破坏网片固定所需的力(拉伸强度)。采用Wilcoxon检验和Spearman等级相关检验进行统计分析。
对于每个固定点数量,经腹壁缝合固定网片的平均拉伸强度显著高于钉合器固定:单个固定点时为67 N对28 N(p<0.001),两个固定点时为115 N对42 N(p<0.001),三个固定点时为150 N对63 N(p<0.05),四个固定点时为151 N对73 N(p<0.05),五个固定点时为150 N对82 N(p<0.05)。每7 cm固定点数量超过3个(固定点之间距离为1.8 cm)时,拉伸强度并未提高。
经腹壁缝合的拉伸强度比钉合器的拉伸强度高2.5倍。因此,在腹腔镜切口疝修补术中,使用经腹壁缝合固定网片似乎更为可取。