Chow T L, Chow T K, Lui Y H, Sze W M, Yuen N W F, Kwok S P Y
Department of Surgery, United Christian Hospital, Kowloon, Hong Kong.
Int J Oral Maxillofac Surg. 2002 Apr;31(2):212-8. doi: 10.1054/ijom.2001.0148.
Lymphoepithelioma-like carcinoma is a rare tumour in the oral cavity and is characterized histologically by non-keratinizing, undifferentiated squamous cell carcinoma with lymphocytic infiltration. Three consecutive cases of intraoral lymphoepithelioma-like carcinoma are reported. A review of the literature reveals a similar biological behaviour to that of nasopharyngeal lymphoepithelioma: a high incidence of cervical nodal spread and remarkable radiosensitivity. Chemotherapy should be considered when nodal or distant metastases are present. The association of the Epstein-Barr virus with this tumour remains unclear but our experience suggests a positive correlation in Chinese individuals.
