Department of Radiation Oncology, Princess Margaret Hospital, Toronto, ON.
Curr Oncol. 2012 Jun;19(3):e177-83. doi: 10.3747/co.19.926.
We present a patient with lymphoepithelioma-like carcinoma (LELC) of the breast whose diagnosis is illustrative of the pathology nuances that must be taken into account to successfully reach correct identification of the disease. We also present an overview of our patient's proposed treatment in the context of 16 other reported LELC cases. Although LELC cases are rare, a sufficient number have been reported to discern the natural history of this pathologic entity and to undertake a review of those cases and of the application of oncologic first principles in their management. Given the potential for locoregional spread and distant metastases in LELC, adjuvant therapy has a role in the treatment of this entity.
我们呈现了一例乳腺淋巴上皮样癌(LELC)患者,其诊断说明了在成功确定疾病时必须考虑的病理细微差别。我们还概述了我们的患者在其他 16 例报告的 LELC 病例背景下提出的治疗方法。虽然 LELC 病例罕见,但已报告了足够数量的病例,以了解该病理实体的自然病史,并对这些病例进行回顾,以及在其管理中应用肿瘤学基本原则。鉴于 LELC 局部区域扩散和远处转移的可能性,辅助治疗在该实体的治疗中具有作用。